"I worry about him. He's got a lot of talent," Guillen said. "It's tough for him, for us, for Venezuelans."
Cabrera is coming off perhaps his best season. He hit .328 with 38 home runs and 126 RBIs in 2010 and finished second to Josh Hamilton in the American League MVP vote.
Cabrera signed an eight-year, $152.3 million extension with the Tigers in 2008. He is under contract until the 2015 season.